Quinolines and derivatives
- (1)
- (1)
- (1)
- (216)
- (6)
- (1)
- (1)
- (40)
- (2)
- (12)
- (48)
- (1)
- (37)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (8)
- (136)
- (1)
- (9)
- (16)
- (1)
- (35)
- (1)
- (1)
- (1)
- (1)
- (1)
- (190)
- (1)
- (1)
- (17)
- (1)
- (18)
- (17)
- (7)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (21)
- (26)
- (2)
- (30)
- (4)
- (6)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (6)
- (5)
- (2)
- (1)
- (11)
- (1)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (25)
- (16)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (4)
- (4)
- (8)
- (2)
- (2)
- (1)
- (1)
- (6)
- (2)
- (1)
- (1)
- (2)
- (1)
- (6)
- (1)
- (20)
- (1)
- (5)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (1)
- (1)
- (2)
- (5)
- (2)
- (4)
- (2)
- (3)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (1)
- (2)
- (4)
- (1)
- (3)
- (3)
- (1)
- (7)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (13)
- (1)
- (2)
- (2)
- (4)
- (3)
- (4)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (19)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (4)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (4)
- (3)
- (2)
- (1)
- (9)
- (5)
- (2)
- (3)
- (3)
- (2)
- (5)
- (6)
- (3)
- (13)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (4)
- (5)
- (4)
- (3)
- (3)
- (7)
- (1)
- (1)
- (2)
- (3)
- (7)
- (5)
- (2)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (4)
- (2)
- (2)
- (6)
- (2)
- (7)
- (4)
- (3)
- (2)
- (2)
- (5)
- (2)
- (1)
- (14)
- (1)
- (1)
- (23)
- (42)
- (24)
- (18)
- (83)
- (3)
- (17)
- (3)
- (5)
- (8)
- (1)
- (6)
- (1)
- (5)
- (1)
- (1)
- (6)
- (5)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (4)
- (1)
- (26)
- (19)
- (70)
- (1)
- (108)
- (3)
- (1)
- (2)
- (60)
- (5)
- (1)
- (1)
- (2)
- (299)
- (2)
- (2)
- (25)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (3)
- (9)
- (3)
- (2)
- (62)
- (2)
- (5)
- (29)
- (3)
- (2)
- (1)
- (1)
- (3)
- (3)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (4)
- (2)
- (1)
- (3)
- (1)
- (2)
- (2)
- (5)
- (3)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (12)
- (4)
- (1)
- (5)
- (3)
- (5)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (3)
- (5)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
Filtered Search Results
Medchemexpress LLC 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diamine | 76927-70-3 | ≥97.0% | 324.41 | 1 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker that can be utilized in the synthesis of PROTACs. It is intended for research use only.
- PEG-based (6 units) PROTAC linker
- Can be used in the synthesis of PROTACs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 287193-07-1 | Ethyl 4-oxooxane-2-carboxylate | ChemScene | MFCD20922879 | 172.180 | C8H12O4 | 95.000 | CCOC(=O)C1CC(=O)CCO1 | 250mg | 572179446
Ethyl 4-oxooxane-2-carboxylate | ChemScene | 287193-07-1 | MFCD20922879 | 172.180 | C8H12O4 | 95.000 | CCOC(=O)C1CC(=O)CCO1 | 250mg | 572179446
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC Fingolimod (FTY720) 162359-56-0 200mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Fingolimod (FTY720 CAS 162359-56-0) is an orally administered sphingosine-1-phosphate (S1P) receptor agonist structurally analogous to natural sphingosine Originally derived from fungal metabolites and initially investigated in organ transplantation fingolimod interacts potently with receptors S1P1 S1P3 S1P4 and S1P5 (EC50 values approximately 0 3 3 1 nM) Its agonism promotes receptor internalization suppressing lymphocyte migration from lymph nodes into the circulation and central nervous system (CNS) Thus fingolimod is studied primarily for autoimmune disorders especially multiple sclerosis due to its effects on lymphocyte trafficking and CNS infiltration
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC Tubastatin A 1252003-15-8 200mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Tubastatin A (CAS 1252003-15-8) is a selective inhibitor of histone deacetylase 6 (HDAC6) an enzyme mediating acetylation states crucial for regulating both histone and non-histone proteins Tubastatin A inhibits HDAC6 with an IC50 of approximately 15 nM and shows minimal activity against class I HDAC isoforms demonstrating greater than 200-fold selectivity In vitro Tubastatin A induces hyperacetylation of -tubulin reduces neuronal cell death inhibits inflammatory cytokines (IL-6 TNF) production in human THP-1 macrophages and decreases NO secretion from mouse Raw 264 7 cells In animal models it exhibits anti-inflammatory and anti-tumor effects Tubastatin A is utilized in research exploring cancer biology inflammation and neuroprotection
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC Resiquimod (R-848) 144875-48-9 10mM (in 1mL DMSO)
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Resiquimod (R-848) is an immunomodulatory small molecule structurally related to imiquimod It functions primarily by activating immune responses via inducing cytokine release In vitro studies with human peripheral blood mononuclear cells (PBMC) indicate that Resiquimod promotes dose-dependent production of cytokines including interferon-alpha (IFN- ) tumor necrosis factor (TNF) interleukin-1 (IL-1 ) and interleukin-6 (IL-6) Mechanistically Resiquimod increases intracellular IL-1 levels and both monocytes and B-cells respond by secreting IFN upon stimulation In addition it elevates mRNA expression of IFN- TNF and IL-8 in treated PBMC relative to untreated controls Resiquimod demonstrates antiviral and antitumor activities in preclinical animal models frequently utilized as an immune response potentiator and Toll-like receptor (TLR) agonist in biomedical investigations (IC50 values typically range in low micromolar)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | 99.9% | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Danofloxacin mesylate is a potent fluoroquinolone antibiotic primarily utilized as a veterinary drug. It exhibits broad-spectrum bactericidal activity by targeting bacterial DNA gyrase, an essential enzyme for bacterial replication. Furthermore, this compound functions as a substrate for ATP-dependent efflux transporters, including P-glycoprotein (P-gp) and Multidrug Resistance-associated Protein 2 (MRP2), which are involved in drug transport mechanisms within cells.
- Fluoroquinolone antibiotic for veterinary use
- Possesses broad-spectrum bactericidal activity
- Inhibits bacterial DNA gyrase
- Acts as a substrate for ATP-dependent efflux transporters
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Dimidium bromide | 518-67-2 | 98.6% | 1 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Dimidium bromide is a biochemical reagent used in life science research as a biological material or organic compound.
- Solid appearance
- Pale purple to purple color
- Store at room temperature, sealed, away from moisture and light
- In solvent, store at -80°C for 1 year or -20°C for 6 months
- Soluble in DMSO (125 mg/mL)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000784008 1 7-HEPTANEDIOL 25G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000784487 QUINOLINE-2-CARBOXYL 25MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000693201 DIHYDROETHIDIUM 1MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000759961 9 10-DIHYDROACRIDINE 1G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Foliglurax monohydrochloride | 2133294-96-7 | 98.57% | 457.97 | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Foliglurax monohydrochloride is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM), with an EC50 of 79 nM. It exhibits an antiparkinsonian effect.
- Highly selective and potent.
- Brain-penetrant mGluR4 PAM.
- EC50 of 79 nM for mGlu4.
- Exhibits antiparkinsonian effect.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Dihydroethidium | 104821-25-2 | 98.83% | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Dihydroethidium, also known as DHE, is a peroxide indicator that penetrates cell membranes to form a fluorescent protein complex with blue fluorescence. After entering cells, it primarily localizes in the cell membrane, cytoplasm, and nucleus, with the strongest staining effect in the nucleus. It produces inherent blue fluorescence and, upon dehydrogenation, combines with RNA or DNA to produce red fluorescence.
- Peroxide indicator
- Penetrates cell membranes
- Forms a fluorescent protein complex with blue fluorescence
- Primarily localized in cell membrane, cytoplasm, and nucleus, strongest staining in the nucleus
- Produces inherent blue fluorescence (Ex 370 nm, Em 420 nm)
- Combines with RNA or DNA after dehydrogenation to produce red fluorescence (Ex 300 nm, Em 610 nm; 535 nm also usable for excitation)
- Solid form
- Pale purple to light pink color
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC LY2886721 1262036-50-9 200mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
LY2886721 (CAS 1262036-50-9) is an orally bioavailable inhibitor of -site amyloid precursor protein cleaving enzyme 1 (BACE1) an aspartyl protease integral to amyloid precursor protein (APP) cleavage and amyloid- (A ) generation LY2886721 inhibits BACE1 activity with an IC50 of approximately 20 3 nM effectively reducing soluble APP and elevating soluble APP in human cell models (HEK293Swe) and neuronal cultures (PDAPP) at IC50 values of 18 7 nM and 10 7 nM respectively In animal models such as PDAPP mice oral LY2886721 administration dose-dependently reduces cerebral A C99 and sAPP levels Due to its BACE1 inhibitory action LY2886721 serves as a valuable tool in Alzheimer s disease research and therapeutic development
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000568663 DIMENHYDRINATE-200MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More